Since taking threelac (4 sachets per day) my raging diarrhea and gale force wind have disappeared, which I have suffered from terribly for years. I have been less tired, getting less migraines, have lost weight (probably due to my thyroid problem improving). I'm not cured of all symptoms but theres been a dramatic improvement. I've also been able to reduce the thyroxine I'm taking. I have been taking other products which have included aerobic oxygen, biokult and active digestive enzymes, so I cant say for sure what proportion of my improvement is down to the threelac, but I believe this has been the primary product that has helped me.