I cannot recommend Fivelac highly enough. I suffered for years with systemic candida which resulted in great vulval & urinary pain/discomfort. I had endless visits to my local Genito-urinary clinic & whilst the prescribed medication eased the symptoms of thrush, no medical professional could help with all my other symptoms. I saw many specialists without result so started to research to help myself........so discovered threelac which worked. And I simply upped it to Fivelac as more of the good bacteria could only do good. The only downside I found was constipation (I do not know if it was definitely caused by the product) which is when I started using the oxy colon cleanse products. If you suffer from constant candida, I would thoroughly recommend Fivelac.