I take 2 x tablets twice a day at the start of my meals morning and evening. The improvement to my digestion was almost immediate. I had been feeling sick and suffering indigestion and bloating. I am now completely free from these symptoms. I also have an arthritic hip and am awaiting a new hip so am in considerable pain. I am taking 2 x tablets between meals as this is recommended for systemic support. Its very difficult to know for sure how much is down to the Veganzyme but my general health is now much improved too.