Initially I found that 1 capsule worked brillianely to begin with. Gradually I had to increase the dosage as lower amounts didn't work any. These days I seem to need 4 capsules. This dosage does work, but I just went to get advice from the The Finchley Clinic, and they recommended me to alternate between Oxy-Powder, Colosan and Mag
7 to prevent my body getting used to the product. Apparently this is a known problem for a small proportion of people, but alternating between the products usually prevents them from gradually becoming less effective.