Having MS my life seemed laxative driven resulting in permanent discomfort. For the past couple of months I have taken one Oxy Powder pill per night and it has the desired effect without any discomfort. They worked gently, with no frightening urgency and one pill seemed to work more or less straight away. As far as I am concerned they are excellent and my life has been much improved. Pity they are not available on NHS prescription! The difference they have made to my life means I will happily keep buying them.