Over 20 years ago, 1992 to be precise, the medical Journal “Epidemiology” published a paper by James Enstron Phd and his colleagues entitled “Vitamin C intake and mortality among a sample of the United States population”. The paper suggested that individuals who regularly supplement their diet with vitamin C have a statistically significant increase in life expectancy over those who consume lower amounts of vitamin C. But this wasn’t really anything that new. Hundreds, in fact probably thousands of books and papers were published before 1992 and many more have been published since then demonstrating the clear and indisputable benefits for immunity, anti-aging, longevity, infection control and countless other benefits again, and again, and yet again of Vitamin C. Amazingly some (though gradually less and less) sceptics still debate whether it is beneficial to supplement with vitamin C at all – on any dosage! I find this “debate” so dated, and ridiculous that I find it astonishing, that anyone would wish to take up such a position, when it is so clearly wrong. This is an argument which they have so demonstrably lost, it really is as silly as when the tobacco companies claimed up to the 1950’s that smoking was good for you, on the basis that it was relaxing.
The discovery of Vitamin C
Around 200 years ago, it was first observed that ‘limeys’ – people who consumed limes, lemons or other citrus on long sea voyages didn’t get scurvy. This is the disease caused by gross Vitamin C deficiency, eventually resulting in death. Although it soon became well known that scurvy could be prevented by consuming limes or any other citrus fruits, the specific compound responsible was not discovered until 1930. That’s when Albert Szent-Györgyi, Professor of Medicinal Chemistry at the University of Szeged in Hungary discovered vitamin C, which he orginally called hexuronic acid. Later on it became known as ascorbic acid, although today there are many ‘ascorbates’ used in food supplements which are all acceptable forms of vitamin C. In 1937 Professor Szent-Györgyi was awarded a Nobel prize for his research, apparently much to the annoyance of other academics who were doing similar research on Vitamin C at the time. One of the first important experiments was with guinea pigs who are similar to humans in that their body’s cannot produce Vitamin C and therefore must get it from diet or supplementation. Cutting a long story short, he found that guinea pigs fed a diet which was enriched with vitamin C flourished. The guinea pigs who were completely deprived of vitamin C developed scurvy-like symptoms. Then they died.
Linus Pauling and the Vitamin C megadose
By the 1970’s Nobel Prize winning chemist Linus Pauling was the most famous (of many) scientists taking up the mantle of vitamin C. In his books “Vitamin C and the Common Cold” and “How to Live Longer and Feel Better”, he claimed that the common cold could be almost entirely prevented by taking large dosages of Vitamin C on a daily basis. We’re talking here about dosages far higher than the feeble RDA (Recommended Daily Allowance), which is the amount described as “the level of necessary intake” – which is effectively the amount you need to take to avoid dropping dead. Of course the conventional medical profession sneered and tried to discredit him, whilst they happily slapped one another on the back. He took huge dosages himself, lived into his mid nineties, and worked until two weeks before his passing. I wonder whether the “experts” who sneered lived as long or as healthily as him? The RDA (recommended daily allowance) for Vitamin C is 60mg a day, which is enough to prevent scurvy. It’s also roughly the amount found in a medium sized orange. Unfortunately though, the amount found in an orange where weeks have gone by from being picked, to being transported to the supermarket, and from the from supermarket the shelves to your stomach typically is much lower than this. However 60mg even from a fresh orange does not provide what most nutritionists consider to be a therapeutic dosage. Linus Pauling himself started on 3000mg (3g) per day, but gradually took more and more until he was taking 18,000mg (18g), of Vitamin C per day! Pauling believed that supplementing with megadoses of Vitamin C led to an improved resistance against essentially all diseases, and he suggested it increased life-span by up to 25 years. True he beleived in supplementing with a number of other nutrients too, but Vitamin C was very much the core nutrient. For more information, read Linus Pauling’s lovely article My Love Affair With Vitamin C (but finish reading this newsletter first!).
A few more functions of Vitamin C
(This list is not by any means comprehensive)
Anti Aging
Vitamin C is an important antioxidant. All antioxidants, by opposing free radical damage, which is considered to be the cause of aging (though I doubt this is the only cause), also oppose aging. Vitamin C is also anti-aging both internally and cosmetically because it also…
Aids collagen synthesis
One of the best known roles of vitamin C is in the formation of collagen. Collagen is the most abundant protein in the body, and is the ‘glue’ that gives integrity to connective tissue, muscles, tendons cartilage, skin, blood vessels, bone and teeth. Obviously Vitamin C is important for all of these tissues to stay in good health. The devastating symptoms of scurvy, which eventually leads to death are mostly due to impaired collagen synthesis. Aging of the skin is in essence a deterioration of the collagen in the skin.
The brain
Vitamin C is involved with dopamine and serotonin production, so it is little wonder that deficiency can be linked to anxiety, an unhealthy response to stress, fatigue, and depression.
Vitamin C and healthy iron levels
Folic acid is activated by vitamin C. Iron works together with Folic acid. It’s uptake from the gut and its utilization in the body is also dependent on vitamin C. Vitamin C deficiency impairs the effectiveness of these important nutrients.
Reduces inflammation
This is the reason high dosages can be very useful for allergy sufferers.
Blood pressure
As little as 0.5g of vitamin C taken every day lowers your blood pressure and reduces the risk of stroke. It’s especially effective in people already diagnosed with high blood pressure, or hypertension. (Source: American Journal of Clinical Nutrition, 2012; 95: 1079-88).
Helps with candida die-off
This is not a benefit which is seen in the medical literature, but I have seen that Vitamin C helps those going through a candida die-off phase. It’s not our core product for this problem (that would be Wild Endive Formula), but it does help.
Which Vitamin C products do I recommend?
Actually I recommend any vitamin C product as being beneficial. However our top selling one, and the one I take myself is Tapioca Vitamin C. My second favourite (which I have also taken on and off) is the extremely pleasant tasting Mixed Ascorbates. For children the most popular one is Fizzy C, although my personal view is that Mixed Ascorbates is equally acceptable for kids. However as we sell around 30 different Vitamin C products, and they all have some unique selling point or other, it’s probably useful for anyone who isn’t sure which one to take to view them all.
Dosage of Vitamin C
Despite some of the sillier press reports that I have occasionally seen, I don’t really think you can harm yourself on any dosage. However there is a maximum beyond which there would be no additional benefit. However it should also be noted that very high dosages of most forms of vitamin C cause loose bowels in some individuals. (Calcium Ascorbate is the most notable exception, and does not seem to cause loose bowels on any dosage – even if you consumed an entire bottle in one go – not that I’d especially recommend anyone to do that).
Studies have shown as little as 500mg per day to be highly beneficial for a range of health issues. However I regard 1g per day, as a basic therapeutic dosage and as much as 15-20g spread out over the day to be useful for acute infections or wherever the immune system may be impaired.
In regarding 1 gram a day as the starting dosage which is sufficient to benefit most people, I have been particularly influenced by the results of two double blind studies. The first in teenage school children which showed a drop of 61% in absenteeism when the pupils were given 1g of vitamin C per day compared to a placebo group, and 64% fewer symptoms in those that did get ill during the trial period. The second with Canadian soldiers, where 68% less sick days were reported compared with a placebo group, also with 1g taken per day. Would these figures be better still if the dosage had been higher?
I do not take the 18g per day suggested by Linus Pauling, but I do take Vitamin C daily and I very rarely get colds or flu’s any more. I used to get just as many as everyone else – in fact probably more for often than most people. When I do get them, which is now very rare, they seem to be very short lived and are vastly less severe (I also up my dosage of Vitamin C to ‘Linus Pauling’ type quantities at that point, and take 2-3 x the label dosage of Oxylift or Oxygen Elements Max). Here is my daily regimen, which I advocate to everyone not just for preventing colds, but for the prevention of all illness, which I take on an ongoing basis.
1) I take Vitamin C the whole year, specifically 1g of Tapioca Vitamin C. Then I get about another gram by taking 2 capsules twice a day of Antioxidant Supreme, which I think is a wonderful wide spectrum antioxidant for immunity and slowing the aging process.
2) I take two capsules a day of Vitamin D 5000iu,
3) Oxylift or the very similar Oxygen Elements Max on the label dosage,*
* Note: ideally, any Oxgen supplement should be taken an hour or more away from taking Vitamin C.
View all Vitamin C products here…and be well over Christmas
Written by Mark Lester, Director, The Finchley Clinic Ltd www.thefinchleyclinic.com